This study provided a critical analysis of the contribution of Cohesion Policy and the European Structural Investment Funds to the Digital Agenda for Europe and the Digital Single Market. Based on the analysis of past and current patterns of ESIF digital investments and selected case studies, this study shows that Cohesion Policy should concentrate where its added value is highest, i.e., on support to the formulation of effective regional digital strategies and the promotion of partnerships between relevant stakeholders, at a regional level and beyond. As part of this study, in-depth analysis and fieldwork were carried out in the following regions/countries: Lithuania (LT); Podkarpackie (PL); Øresund (Cross-border DK-SE); Murcia (ES); Gonesse, Ile-de-France (FR); Emilia Romagna (IT). The final report is available on the Client’s website.